It improves learning ability and memory, working on all phases of processing: the initial processing of information, consolidation, extraction. It prevents the development of amnesia induced by electric shock, blockade of central cholinergic structures glutamatergic receptor systems, deprivation of paradoxical sleep phase.
Neuroprotective (protective) action winstrol before and after is to increase the stability of brain tissue to damaging influences (trauma, hypoxia, electroconvulsive, toxic) and the weakening of the degree of damage neurons in the brain. The drug reduces the amount of focus on thrombotic stroke models and prevents death of neurons in tissue culture of the cerebral cortex and cerebellum, subjected to the action of neurotoxic concentrations of glutamate, free radical oxygen.
Has an antioxidant effect, an antagonistic effect on the excess calcium effects, improves the rheological properties of blood, having antiagregatine, fibrinolytic, anticoagulant properties.
Nootropic effect of the drug is associated with the formation tsikloprolilglitsina similar in structure to endogenous cyclic dipeptide possessing antiamnestic activity and the presence holinopozitivnogo action.
Noopept ® increases the amplitude transcallosal response, facilitating associations between brain hemispheres at . cortical structures
contributes to the restoration of memory and other cognitive functions, disturbed as a result of the damaging effects -. cerebral trauma, local and global ischemia, prenatal damage (alcohol, hypoxia)
The therapeutic effect of the drug in patients with organic disorders of the central nervous system is manifested starting from 5- 7 days of treatment. First implemented winstrol before and after in the existing spectrum of activity anxiolytic and stimulating light effects, manifested in the reduction or disappearance of anxiety, irritability, affective lability, sleep disorders. After 14-20 days of therapy revealed a positive effect of the drug on cognitive function, attention and memory options.
Has vegetonormalizuyuschim action, it helps to reduce headaches, orthostatic disorders, tachycardia.
In case of cancellation of the drug is observed withdrawal.
Do not have a damaging effect on the internal organs ; It does not lead to a change in the cellular composition of the blood and biochemical parameters of blood and urine; has no immunotoxic, teratogenic, does not exhibit mutagenic properties.
Ethyl N-phenylacetyl-L-prolylglycine, absorbing in the gastro-intestinal tract unaltered enters the systemic circulation, penetrates the blood-brain barrier, the brain is determined in large concentrations than in the blood. Time to maximum winstrol before and after concentration is on average 15 minutes. The half-life of blood plasma -. 0.38 h partly preserved in unchanged form, partially metabolized with the formation of phenylacetic acid, and fenilatsetilprolina tsikloprolilglitsina. It has a high relative bioavailability (99.7%), not accumulates in the body, it does not cause drug dependence.
Violations of memory, attention and other cognitive functions, and emotionally labile disorder (including elderly patients) when:
- consequences of traumatic brain injury
- commotion syndrome
- cerebral vascular disease (encephalopathy different genesis)
- asthenic disorders
- other conditions with signs of reducing intellectual productivity
Pregnancy, lactation.Age up to 18 years.Hypersensitivity to the drug.Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.Expressed human liver and kidneys.
Dosing and Administration
Noopept ® is used in, after a meal.Treatment starts with the use of the drug at a dose of 20 mg, distributed over two steps of 10 mg per day (morning and afternoon).In case of insufficient efficacy and good tolerability of the drug dose was increased to 30 mg (see. “Special Instructions”), distributing it to the three steps of 10 mg per day.Do not take the medication within 18 hours.The duration of a course of treatment is 1.5 – 3 months.Repeated treatment may be carried out after 1 month if necessary.
If necessary, increase the dose (30 mg / day), with prolonged use, and while the use of other drugs, the emergence of adverse events or deterioration should consult a doctor.
Specific manifestations of overdose are not established.
Allergic reactions are possible.In patients with hypertension, mostly severe, rise in blood pressure may occur in patients receiving the drug.
Interaction with other drugs not identified interaction winstrol before and after with alcohol, drugs and antihypertensive drugs and drugs stimulating effect.